How you manage the rose depends a bit on what type. Assuming it is a Hybrid Tea, Grandiflora, or similar, they respond well to pruning. In the fall, you want to Prune them back to prevent wind damage. If you can, cut the canes back to 12-18 inches, remove old or dead canes, remove crossing/rubbing canes, and prune for shape. In the spring, you want to cut back anything that dies over the winter once it starts to leaf out and you can see where the living canes end. Throughout the growing season, you should deadhead as needed. You can cut back canes when deadheading to the first 5-leaf cluster. You can cut them back farther if you want.
If you have a shrub rose, then you generally want to prune less - though you can prune them just like other roses. You can even take a shrub trimmer to them in the spring like you would for a boxwood. Knockout roses are a common shrub rose.
If you know what specific rose you have (they usually have names like Chrysler Imperial, Double Delight, Distant Drums, etc.), I can give you better advice.